Cathepsin K Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Cathepsin K antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Cathepsin K |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Cathepsin K(CTSK) detection. Tested with WB, IHC-P in Human. Background: Cathepsin K, abbreviated CTSK, is an enzyme that in humans is encoded by the CTSK gene. It is mapped to 1q21. The protein encoded by this gene is a lysosomal cysteine protease involved in bone remodeling and resorption. And this protein, which is a member of the peptidase C1 protein family, is expressed predominantly in osteoclasts. Additionally, the enzyme's ability to catabolize elastin, collagen, and gelatin allow it to break down bone and cartilage. This catabolic activity is also partially responsible for the loss of lung elasticity and recoil inemphysema. Cathepsin K inhibitors, such as odanacatib, show great potent |
| Immunogen | Immunogen: E Coli-derived human Cathepsin K recombinant protein (Position: A115-M329). Human Cathepsin K shares 86.9% and 88.8% amino acid (aa) sequence identity with mouse and rat Cathepsin K, respectively. Ig Type: Rabbit IgG |
| Other Names | [Cathepsin K; Cathepsin K; Cathepsin O; Cathepsin O1; Cathepsin O2; Cathepsin X; CATK_HUMAN; CTS02; Ctsk; CTSO; CTSO1; CTSO2; MGC23107; PKND; PYCD; cathepsin K], [CTSK; CTSK; CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2; CTSO; CTSO2] |
| Gene, Accession # | Gene ID: 1513, NCBI: NP_000387.1, UniProt: P43235 |
| Catalog # | MBS178060 |
| Price | $315 |
| Order / More Info | Cathepsin K Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: CTSK cathepsin K. 2. Inaoka T, Bilbe G, Ishibashi O, Tezuka K, Kumegawa M, Kokubo T (January 1995). Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone. Biochem. Biophys. Res. Commun. 206 (1): 89-96. 3. Motyckova G, Fisher DE (2003). Pycnodysostosis: role and regulation of cathepsin K in osteoclast function and human disease.. Curr. Mol. Med. 2 (5): 407-21. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies