Securin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Securin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Securin(PTTG1) detection. Tested with WB in Human. Background: Securin, also known as pituitary tumor-transforming 1 or EAP1 is a protein that in humans is encoded by the PTTG1 gene. PTTG1 gene is mapped to 5q33.3. The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex(APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Securin (146-161aa LMILDEERELEKLFQL), different from the related rat sequence by four amino acids, and from the related mouse sequence by five amino acids. |
| Other Names | [Securin; pituitary tumor-transforming 1; EAP1; PTTG; TUTR1; Hpttg; TUMOR-TRANSFORMING 1; Esp1-associated protein; ESP1-ASSOCIATED PROTEIN 1; Tumor-transforming protein 1; Pituitary tumor-transforming gene 1 protein], [PTTG1; PTTG1; EAP1; PTTG; HPTTG; TUTR1; EAP1; PTTG; TUTR1; Tumor-transforming protein 1; hPTTG] |
| Gene, Accession # | [PTTG1], Gene ID: 9232, NCBI: O95997.1, UniProt: O95997 |
| Catalog # | MBS176976 |
| Price | $280 |
| Order / More Info | Securin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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