TNFRSF18 Picoband Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNFRSF18 Picoband
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionDescription: Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.Protein Function: Receptor for
ImmunogenImmunogen: E Coli-derived human TNFRSF18 recombinant protein (Position: Q26-P162). Subcellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Other Names[Tumor necrosis factor receptor superfamily member 18; Activation-inducible TNFR family receptor; Glucocorticoid-induced TNFR-related protein; CD357; TNFRSF18; AITR; GITR; UNQ319/PRO364]
Gene, Accession #[TNFRSF18], Gene ID: 8784, NCBI: NP_004186.1, UniProt: Q9Y5U5
Catalog #MBS1750814
Price$280
Order / More InfoTNFRSF18 Picoband Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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