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Antigenic Specificity | Profilin1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. |
Immunogen | Immunogen: A synthesized peptide derived from human Profilin1. Subcellular Localization: Cytoplasm, cytoskeleton. Tissue Specificity: Expressed in epididymis (at protein level). |
Other Names | [Profilin-1; Epididymis tissue protein Li 184a; Profilin I; PFN1], [PFN1; PFN1; ALS18] |
Gene, Accession # | [PFN1], Gene ID: 5216, NCBI: NP_005013.1, UniProt: P07737 |
Catalog # | MBS179670 |
Price | $160, $340, $340 |
Order / More Info | Profilin1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |