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Antigenic Specificity | Human Cold-inducible RNA-binding protein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. |
Immunogen | Immunogen: Recombinant human Cold-inducible RNA-binding protein (1-172aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161012 / sc-133460 |
Other Names | [A18 hnRNP; Glycine-rich RNA-binding protein CIRP; CIRBP; A18HNRNP; CIRP;], [CIRBP; CIRBP; CIRP; A18HNRNP; CIRP] |
Gene, Accession # | [CIRBP], Gene ID: 1153, NCBI: NP_001271.1, UniProt: Q14011 |
Catalog # | MBS1498731 |
Price | $120, $160 |
Order / More Info | Human Cold-inducible RNA-binding protein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |