RIG-1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | RIG-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | DEAE purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RIG-1 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG-1) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG-1 activates the kinases TBK1 and IKKε through the adaptor protein IPS-1. These kinases then phosphorylate the transcription factors IRF-3 and IRF-7 which are essential for the expression of type-I interferons. RIG-1 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus. |
| Immunogen | Immunogen: RIG-1 antibody was raised against human GST-tagged RIG-1 protein. Buffer: RIG-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [RIG-1; RIGI; RIG-I; RLR-1; Probable ATP-dependent RNA helicase DDX58; DEAD box protein 58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58], [DDX58; DDX58; RIGI; RIG-I; RLR-1; RLR-1; RIG-1; RIG-I] |
| Gene, Accession # | [DDX58], Gene ID: 23586, NCBI: O95786.2, UniProt: O95786 |
| Catalog # | MBS150656 |
| Price | $375 |
| Order / More Info | RIG-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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