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Antigenic Specificity | COMT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total COMT antibody. Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human COMT. |
Other Names | [HEL-S-98n] |
Gene, Accession # | [COMT], Gene ID: 1312, NCBI: NP_000745.1, UniProt: P21964 |
Catalog # | MBS9406728 |
Price | $255 |
Order / More Info | COMT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |