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Antigenic Specificity | Mouse T-cell Immunoglobulin Mucin-2 (TIM-2) |
Clone | [5B23] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects mouse of TIM-2 in Western blotting. This antibody does not cross-react with mouse TIM-1 and TIM-3. TIM-2 is a type I membrane protein and is a member of the TIM protein family. TIM-2 has an immunoglobulin variable region-like domain followed by a mucin-like domain in its extracellular region.This protein family is characterized by their conserved immunoglobulin and mucin domains, as well as by their expression on activated T cells. TIM-2 is a receptor for Semaphorin 4A, which is expressed on dendritic cells and B cells. Semaphorin 4A has been shown to enhance T cell activation. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant TIM-2. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
Other Names | [mouse TIM-2 [T-cell Immunoglobulin Mucin-2] (#5B23)], [Timd2; Timd2; G9D3; Tim2; TIM-2; C78111; AA816106; AU019358; AU019662; Tim2; TIMD-2; TIM-2] |
Gene, Accession # | [TIM-2], Gene ID: 171284, NCBI: NP_001154827.1, UniProt: Q8R183 |
Catalog # | MBS690187 |
Price | $490 |
Order / More Info | Mouse T-cell Immunoglobulin Mucin-2 (TIM-2) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |