AURKA Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-AURKA antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | AURKA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Aurora A (AIK) is a cell cycle-regulated Ser/Thr protein kinase that is overexpressed in many tumor cell lines (1-3). Phosphorylation of Aurora A at Thr288 within the kinase activation loop results in a significant increase in its activity and may target the protein for proteasomal degradation during mitosis (4). The closely-related kinase Aurora B (AIM1) has been implicated in multiple mitotic events (5), and siRNA silencing of Aurora B expression results in reduced histone H3 phosphorylation, aberrant chromosome alignment/segregation, and altered survivin localization (6). |
| Immunogen | Immunogen: A synthetic peptide of human AURKA Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [AIK; ARK1; AURA; AURORA2; BTAK; MGC34538; STK15; STK6; STK7] |
| Gene, Accession # | [AURKA], Gene ID: 6790, NCBI: NP_001310232.1, UniProt: O14965 |
| Catalog # | MBS8504304 |
| Price | $310 |
| Order / More Info | AURKA Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Bischoff, J.R. et al. (1998) EMBO J 17, 3052-65. 2. Zhou, H. et al. (1998) Nat Genet 20, 189-93. 3. Sen, S. et al. (1997) Oncogene 14, 2195-200. 4. Walter, A.O. et al. (2000) Oncogene 19, 4906-16. 5. Kallio, M.J. et al. (2002) Curr Biol 12, 900-5. 6. Hauf, S. et al. (2003) J Cell Biol 161, 281-94. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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