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Antigenic Specificity | NFKBIZ |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Immunogen | Immunogen: Rabbit polyclonal NFKBIZ (1) antibody was raised against a peptide from C terminal residues of human NFKBIZ protein. |
Other Names | [NF-kappa-B inhibitor zeta isoform b; NF-kappa-B inhibitor zeta; NF-kappa-B inhibitor zeta; I-kappa-B-zeta; IL-1 inducible nuclear ankyrin-repeat protein; Ikappa B-zeta variant 3; IkappaB-zeta; ikB-zeta; ikappaBzeta; molecule possessing ankyrin repeats induced by lipopolysaccharide; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; I-kappa-B-zeta; IkB-zeta; IkappaBzeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Molecule possessing ankyrin repeats induced by lipopolysaccharide; MAIL], [NFKBIZ; NFKBIZ; IKBZ; INAP; MAIL] |
Gene, Accession # | [NFKBIZ], Gene ID: 64332, NCBI: NP_001005474.1 |
Catalog # | MBS416207 |
Price | $230 |
Order / More Info | NFKBIZ Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Lorenz,J., Zahlten,J., Pollok,I. et al. Legionella pneumophila-induced IkappaBzeta-dependent expression of interleukin-6 in lung epithelium. Eur. Respir. J. 37 (3), 648-657 (2011). |