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Antigenic Specificity | DNMT3A (Center R478) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DNMT3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from the Central region of human DNMT3A. Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
Immunogen | n/a |
Other Names | [DNA (cytosine-5)-methyltransferase 3A; Dnmt3a; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; MHsaIIIA; DNMT3A] |
Gene, Accession # | [DNMT3A], Gene ID: 1788, NCBI: NP_783328.1, UniProt: Q9Y6K1 |
Catalog # | MBS9217086 |
Price | $165, $370 |
Order / More Info | DNMT3A (Center R478) Antibody from MYBIOSOURCE INC. |
Product Specific References | Holz-Schietinger, C., et al. J. Biol. Chem. 285 (38):29091-29100 (2010). Kelemen, L.E., et al. Cancer Epidemiol. Biomarkers Prev. 19 (7):1822-1830 (2010). Park, C.W., et al. J Cardiovasc Transl Res 3 (3):290-295 (2010). Haggarty, P., et al. PLoS ONE 5 (6), E11329 (2010). Zhao, Z., et al. J. Biomed. Biotechnol. 2010, 737535 (2010). |