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Antigenic Specificity | BCL7A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total BCL7A protein. This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.Zani V.J., Blood 87:3124-3134(1996).Ota T., Nat. Genet. 36:40-45(2004).Matsuoka S., Science 316:1160-1166(2007). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human BCL7A. |
Other Names | [B-cell CLL/lymphoma 7 family member A; B-cell CLL/lymphoma 7A; B-cell CLL/lymphoma-7; BCL7; BCL7A] |
Gene, Accession # | [BCL7A], Gene ID: 605, NCBI: NP_001019979.1, UniProt: Q4VC05 |
Catalog # | MBS9413399 |
Price | $200, $255 |
Order / More Info | BCL7A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |