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Antigenic Specificity | Human PARP1 / PARP |
Clone | [A6.4.12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) - Paraffin/Frozen, Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes poly (ADP-ribose) polymerase 1 (PARP-1), a ~116kD nuclear enzyme cleaved during apoptosis. PARP-1, a caretaker enzyme, is involved in DNA damage repair, plays roles in diabetes pathophysiology and tumor proliferation.). As well as protecting cells from genomic instability, PARP-1 is involved in the development of both inflammatory and immune responses, and cell death by apoptosis and necrosis. Targets PARP-1, an enzyme which represents a promising target for new developments in therapeutic treatment of immune mediated diseases. PARP-1 has considerable potential for delivering selective tumor cell killing while sparing normal cells. |
Immunogen | Immunogen: PARP1 antibody was raised against human PARP. Immunogen Species: PARP1 antibody was raised against Human. |
Other Names | [PARP1 / PARP (clone A6.4.12) IHC-plus; PARP1; ADPRT; ADP-ribosyltransferase NAD(+); Adp-ribosyltransferase; ADPRT1; ARTD1; ADPRT 1; Poly(ADP-ribose) synthetase; Poly(ADP-ribosyl)transferase; PARP; Poly [ADP-ribose] polymerase 1; PADPRT-1; PARP-1; Poly (ADP-ribose) polymerase 1; Human PARP1; PARP], [PARP] |
Gene, Accession # | [PARP1], Gene ID: 142, NCBI: NP_001609.2, UniProt: P09874 |
Catalog # | MBS246444 |
Price | $530 |
Order / More Info | Human PARP1 / PARP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |