FAIM2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAIM2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: FAIM2 antibody detects endogenous levels of total FAIM2. Function: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development.Subunit Structure: Interacts with FAS/TNFRSF6 and BAX.Similarity: Belongs to the BI1 family. LFG subfamily.
ImmunogenImmunogen: A synthesized peptide derived from human FAIM2 Subcellular Location: Cell Membrane. Cell Junction > Synapse > Postsynaptic Cell Membrane. Tissue Specificity: Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus.
Other Names[FAIM 2; Faim2; FAIM2_HUMAN; Fas apoptotic inhibitory molecule 2; KIAA0950; LFG; Lifeguard; Neural membrane protein 35; NGP 35; NGP35; NMP 35; NMP35; Protein lifeguard; TMBIM 2; TMBIM2; Transmembrane BAX inhibitor motif containing 2; Transmembrane BAX inhibitor motif containing protein 2; Transmembrane BAX inhibitor motif-containing protein 2]
Gene, Accession #[FAIM2], Gene ID: 23017, NCBI: NP_036438.2, UniProt: Q9BWQ8
Catalog #MBS9609832
Price$240, $280
Order / More InfoFAIM2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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