Mouse CD62L/L-selectin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD62L/L-selectin |
| Clone | [MEL-14] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD62L/L-selectin, Mr 90 kDa. CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and Epidermal Growth Factor-like domains.^1, 2 It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes.^1, 2 In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes and eosinophils.^3-7 This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation.^1, 2, 7-9 Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activatio |
| Immunogen | Immunogen: C3H/eb cloned mouse B lymphoma 38C-13 |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS673415 |
| Price | $260 |
| Order / More Info | Mouse CD62L/L-selectin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Gallatin, W.M., I.L. Weissman, and E.C. Butcher. 1983. Nature 304:30.2. Siegelman, M.H., I.C. Cheng,, I.L. Weissman, and E.K. Wakeland. 1990. Cell 61:611.3. Reichert, R.A., I.L. Weissman, and E.C. Butcher. 1986. J. Immunol. 136:3521.4. Reichert, R.A., I.L. Weissman, and E.C. Butcher. 1986. J. Immunol. 136:3529.5. Reichert, R.A., L. Jerabek, W.M. Gallatin, E.C. Butcher, and I.L. Weissman. 1986. J. Immunol. 136:3535.6. Iwabuchi, K., J. Ohgama, K. Ogasawara, C. Iwabuchi, I. Negishi, R.A. Good, and K. Onoe. 1991. Immunobiology 182:161.7. Lewinsohn, D.M., R.F. bargatze, and E.C. Butcher. 1987. J. Immunol. 138:4313.8. Pizcueta, P., and F.W. Luscinskas. 1994. Am. J. Pathol. 145:461.9. Ley, K., D.C. Bullard, M.L. Arbones, R. Bosse, D. Vestweber, T.F. Tedder, and A.L. Beaudet. 1995. J. Exp. Med. 181:669.10. Jung, T.M., W.M. Gallatin, I.L. Weissman, and M.O. Dailey. 1988. J. Immunol. 141:4110.11. Kishimoto, T.K., M.A. Jutila, E.L. berg, and E.C. Butcher. 1989. Science 245:1238.12. Mobley, J.L., and M.O. Dailey. 1992. J. Immunol. 148:2348.13. Sprent, J., and D.F. Tough. 1994. Science 265:1395. |
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