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Antigenic Specificity | ADRA1B (Center), 270-297 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rabbit, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human ADRA1B. Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogen |
Immunogen | n/a |
Other Names | [Alpha-1B adrenergic receptor; Alpha-1B adrenoreceptor; Alpha-1B adrenoceptor; ADRA1B] |
Gene, Accession # | [ADRA1B], Gene ID: 147, NCBI: NP_000670.1, UniProt: P35368 |
Catalog # | MBS9209000 |
Price | $165, $370 |
Order / More Info | ADRA1B (Center), 270-297 Antibody from MYBIOSOURCE INC. |
Product Specific References | Mathias,R.A., J. Allergy Clin. Immunol. 125 (2), 336-346 (2010) Jensen,B.C., Circ Heart Fail 2 (6), 654-663 (2009) Gratacos,M., Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) |