TLR4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TLR4 |
| Clone | [HTA125] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | 0.025 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TLR4 (Toll-like receptor-4) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. It primarily mediates cellular signaling induced by Gram-negative bacteria. TLR4 is highly specific for LPS and it is associated with CD14, a co-receptor for LPS. The downstream signaling pathway of TLR4 leads to the activation of NF-kappaB through myeloid differentiation protein (MyD88) and IL-1 receptor-associated kinase in various cell types. Keratinocytes express TLR4 at the mRNA and protein levels whereas TLR4 are also present in the normal human epidermis in vivo and their expression is regulated by microbial components. TLR4 is expressed on CD4+ T cells as well, the f |
| Immunogen | Immunogen Information: This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen. |
| Other Names | [TLR4], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10] |
| Gene, Accession # | [TLR4], Gene ID: 7099, NCBI: O00206.2, UniProt: O00206 |
| Catalog # | MBS668473 |
| Price | $145, $290 |
| Order / More Info | TLR4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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