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Antigenic Specificity | ITPK1 (N-term), 28-54 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ITPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of human ITPK1. Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6) |
Immunogen | n/a |
Other Names | [Inositol-tetrakisphosphate 1-kinase; Inositol 1,4-trisphosphate 5/6-kinase; Inositol-triphosphate 5/6-kinase; Ins(1,4)P(3) 5/6-kinase; ITPK1] |
Gene, Accession # | [ITPK1], Gene ID: 3705, NCBI: NP_001136065.1, UniProt: Q13572 |
Catalog # | MBS9213174 |
Price | $165, $370 |
Order / More Info | ITPK1 (N-term), 28-54 Antibody from MYBIOSOURCE INC. |
Product Specific References | Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Yoshida, T., et al. Int. J. Mol. Med. 24(4):539-547(2009) Chamberlain, P.P., et al. J. Biol. Chem. 282(38):28117-28125(2007) |