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Antigenic Specificity | Human IL-17A |
Clone | [4C1] |
Host Species | Mouse |
Reactive Species | human, others no tested. |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reactive with recombinant human IL-17A. IL-17A is an inflammatory cytokine produced by Th17 cells, a newly characterised group of CD4 T help cells that plays a role in autoimmune diseases and chronic inflammatory diseases. IL-23 is the main inducer of Th17 cell development. Other cytokines such as TGF-beta, IL-6 and IL-21 were also found to contribute to the procedure. IL-17A belongs to the IL-17 family which includes IL-17A, IL-17B, IL-17C, IL-17D and IL-17E. IL-17, like interferon-gamma, is a potent mediator of delayed-type reaction. IL-17 induces the secretion of many other pro-inflammatory cytokines and chemokines such as IL-6, IL-8, GM-CSF, G-CSF, TGF-beta, TNF-alpha, GRO-alpha, and MCP-1. IL-17 stimulates the expression of NF-kappaB, |
Immunogen | Immunogen: Purified, human cell expressed recombinant human IL-17A. Fusion Myeloma: SP2/0. |
Other Names | [mAb Human IL-17A clone 4C1; Mouse to human interleukin-17A (IL-17A)], [IL17A; IL17A; IL17; CTLA8; IL-17; CTLA-8; IL-17A; CTLA8; IL17; IL-17; IL-17A; CTLA-8] |
Gene, Accession # | [IL-17A], Gene ID: 3605, NCBI: NP_002181.1, UniProt: Q16552 |
Catalog # | MBS592430 |
Price | $490 |
Order / More Info | Human IL-17A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |