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Antigenic Specificity | IPO7 (N-term), 142-169 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IPO7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the N-terminal region of human IPO7. The importin-alpha/beta complex and the GTPase Ran mediatenuclear import of proteins with a classical nuclear localizationsignal. The protein encoded by this gene is a member of a class ofapproximately 20 potential Ran targets that share a sequence motifrelated to the Ran-binding site of importin-beta. Similar toimportin-beta, this protein prevents the activation of Ran's GTPaseby RanGAP1 and inhibits nucleotide exchange on RanGTP, and alsobinds directly to nuclear pore complexes where it competes forbinding sites with importin-beta and transporti |
Immunogen | n/a |
Other Names | [Importin-7; Imp7; Ran-binding protein 7; RanBP7; IPO7; RANBP7] |
Gene, Accession # | [IPO7], Gene ID: 10527, NCBI: NP_006382.1, UniProt: O95373 |
Catalog # | MBS9208072 |
Price | $165, $370 |
Order / More Info | IPO7 (N-term), 142-169 Antibody from MYBIOSOURCE INC. |
Product Specific References | Huang, S., et al. Biosci. Rep. 30(3):159-168(2010) Chachami, G., et al. Biochem. Biophys. Res. Commun. 390(2):235-240(2009) Adeyemo, A., et al. PLoS Genet. 5 (7), E1000564 (2009) : Zaitseva, L., et al. Retrovirology 6, 11 (2009) : Yao, X., et al. J. Biol. Chem. 283(33):22867-22874(2008) Olsen, J.V., et al. Cell 127(3):635-648(2006) Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005) Dean, K.A., et al. J. Cell. Sci. 114 (PT 19), 3479-3485 (2001) : Jakel, S., et al. EMBO J. 18(9):2411-2423(1999) Paraskeva, E., et al. J. Cell Biol. 145(2):255-264(1999) Jakel, S., et al. EMBO J. 17(15):4491-4502(1998) Gorlich, D., et al. J. Cell Biol. 138(1):65-80(1997) |