CD6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD6
Clone[SPV-L14]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF)
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DescriptionSpecificity: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular -scavenger receptor cysteine-rich- (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
ImmunogenImmunogen: CD8+ cytotoxic T-cell clone
Other Names[T12; TP120], [CD6; CD6; TP120]
Gene, Accession #[CD6], Gene ID: 923, NCBI: NP_001241679.1, UniProt: P30203
Catalog #MBS438533
Price$190, $340, $340
Order / More InfoCD6 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKamoun et al., J. Immunol. 127, 987, 1981 Reinherz et al., Proc. Nat. Acad. Sci. 79, 6047, 1982 Yssel, H., de Vries, J.E., Borst, J. and Spits, H. Distribution and functional analysis of a 120-130 kDa T cell surface antigen. Cell. Immunol. 105: 161-173, 1987. Bazil, V et. al. 1989. Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. Folia. Biol. 35:289-297
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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