MYD88 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | MYD88 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated ac |
| Immunogen | Immunogen: Recombinant protein of human MyD88 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [MYD88D] |
| Gene, Accession # | [MYD88], Gene ID: 4615, NCBI: NP_001166037.1, UniProt: Q99836 |
| Catalog # | MBS8505657 |
| Price | $310 |
| Order / More Info | MYD88 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Akira, S. (2003) J BiolChem 278, 38105-8. 2. Beutler, B. (2004) Nature 430, 257-63. 3. Dunne, A. and O'Neill, L.A. (2003) Sci STKE 2003, re3. 4. Harroch, S. et al. (1995) Nucleic Acids Res. 23, 3539-46. 5. Hardiman, G. et al. (1996) Oncogene 13, 2467-75. 6. Bonnert, T.P. et al. (1997) FEBS Lett. 402, 81-4. 7. Medzhitov, R. et al. (1998) Mol. Cell 2, 253-8. 8. Wesche, H. et al. (1997) Immunity 7, 837-47. 9. Muzio, M. et al. (1997) Science 278, 1612-1615. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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