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Antigenic Specificity | LAS1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: horse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LAS1L Antibody detects endogenous levels of LAS1L. Description: Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.Subunit Structure: Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6 |
Immunogen | Immunogen: A synthesized peptide derived from human LAS1L. |
Other Names | [dJ475B7.2; FLJ12525; FLJ30133; FLJ45274; LAS1 like (S. cerevisiae); Las1 like; LAS1L; LAS1L_HUMAN; Protein LAS1 homolog; Ribosomal biogenesis protein LAS1L; RP3 475B7.2] |
Gene, Accession # | [LAS1L], Gene ID: 81887, NCBI: NP_001164120.1, UniProt: Q9Y4W2 |
Catalog # | MBS9611873 |
Price | $240, $280 |
Order / More Info | LAS1L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |