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Antigenic Specificity | Bassoon |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | phycoerythrin (RPE) conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~420kDa, corresponding to the molecular mass of Bassoon. Multiple isoforms can be detected. No cross-reactivity to Piccolo. Scientific Background: Bassoon (1) is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic de |
Immunogen | n/a |
Other Names | [BSN; ZNF231; Neuronal double zine finger protein], [BSN; BSN; ZNF231; KIAA0434; ZNF231] |
Gene, Accession # | Gene ID: 8927, NCBI: NP_003449.2, UniProt: Q9UPA5 |
Catalog # | MBS804935 |
Price | $435 |
Order / More Info | Bassoon Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Anna Dondzillo et al., (2010) J. Comp Neur, 518(7): 1008-1029. |