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Antigenic Specificity | Human CD81 |
Clone | [1.3.3.22] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells. |
Immunogen | n/a |
Other Names | [Human CD81; CD81 antigen; CD81; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative 1.Tetraspanin-28; Tspan-28; APA1; TSPAN28] |
Gene, Accession # | [CD81], Gene ID: 975, NCBI: NP_001284578.1, UniProt: P60033 |
Catalog # | MBS2553861 |
Price | $75, $135 |
Order / More Info | Human CD81 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Menno C, et al. 2010. J. Clin. Invest. 4:1265. 2. Fearon D, et al. 1995. Annu. Rev. Immunol. 13:127. 3. Wright M, et al. 1994. Immunol. Today 15:588. |