Edit |   |
---|---|
Antigenic Specificity | BAX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported f |
Immunogen | Immunogen: A synthetic peptide of human BAX |
Other Names | [BCL2L4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: NP_001278357.1, UniProt: Q07812 |
Catalog # | MBS2547964 |
Price | $150, $225, $360 |
Order / More Info | BAX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |