Phosphotyrosine Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhosphotyrosine
Clonepolyclonal
Host SpeciesRabbit
Reactive SpeciesGeneral
Isotypen/a
FormatAPC-Cy7 conjugate
Size0.4 mL
Concentration0.25 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA)
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DescriptionDetects proteins phosphorylated on tyrosine residues. Does not cross-react with phosphoserine or threonine. Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of th
ImmunogenImmunogen: Phosphotyrosine conjugated to KLH
Other Names[Rabbit Phosphotyrosine; Phospho-tyrosine; Phosphotyrosine]
Gene, Accession #n/a
Catalog #MBS8004235
Price$525
Order / More InfoPhosphotyrosine Antibody from MYBIOSOURCE INC.
Product Specific References1. Goto H. et al. (2005) Nature Cell Biology 8: 180-187. 2. Blume-Jensen P. and Hunter T. (2001) Nature 411: 355-365. 3. Downward J. (2001) Nature 411: 759-762. 4. Pawson T. and Saxton T.M. (1999) Cell 97: 675-678. 5. Frackelton A.R. Jr., Ross A.H., and Eisen H.N. (1983) Mol Cell Biol. 3: 1343-1352. 6. Ross A.H., Baltimore D., and Eisen H.N. (1981) Nature 294: 654-656. 7. Ostrovsky PC. (1995) Genes Dev. 9(16): 2034-2041.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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