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Antigenic Specificity | TRAF3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily and the interleukin-1 receptor. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. Recent molecular cloning studies have lead to identification of six TRAFs. TRAF3, originally named CRAF1, interacts directly with the CD40 cytoplasmic tail through a region of similarity to the tumor necrosis factor-alpha receptor-associated factors. TRAF3 binds only a single site, which contains the sequence PEQET, whereas TRAF1 and TRAF2 are capable of binding to either the PEQET site or an additional downstream dom |
Immunogen | Immunogen: TRAF3 antibody was raised in Rabbit using synthetic peptide corresponding to residues around amino acid 107 of human TWEAK Receptor as the immunogen. |
Other Names | [Rabbit TRAF3; TRAF3; TRAF3; TRAF-3; TRAF3; TNFR1; MGC11078; TRAF 3; TRAF-3; Hs.89862; TRAF-3; TRAF 3] |
Gene, Accession # | [TRAF3] |
Catalog # | MBS5311365 |
Price | $430 |
Order / More Info | TRAF3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |