EGFR (Matuzumab); Human IgG1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | EGFR (Matuzumab); Human IgG1 |
| Clone | monoclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein A purified |
| Size | 0.2 mg |
| Concentration | n/a |
| Applications | Block; Flow Cytometry (FC/FACS); Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody to detect EGFR in human samples. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF; TGFA/TGF-alpha; amphiregulin; epigen/EPGN; BTC/betacellulin; epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK; PI3 kinase-AKT; PLCgamma-PKC and STATs modules. May also acti |
| Immunogen | Immunogen: Domain III of the extracellular domain of human EGRF. |
| Other Names | [Epidermal Growth Factor Receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1], [EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; ERBB; ERBB1; HER1] |
| Gene, Accession # | [EGFR], Gene ID: 1956, NCBI: NP_005219.2, UniProt: P00533 |
| Catalog # | MBS845968 |
| Price | $655 |
| Order / More Info | EGFR (Matuzumab); Human IgG1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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