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Antigenic Specificity | XAB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.7mg/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total XAB2 protein. HCNP, also known as XAB2 (Xeroderma pigmentosum group A (XPA) binding protein 2), HCRN, SYF1 or NTC90, is a nuclear protein that participates in transcription, transcription-coupled repair (TCR) and pre-mRNA splicing. It contains fifteen tetratricopeptide repeat motifs and associates with nucleotide excision repair machinery. More specifically, HCNP associates with Cockayne syndrome group A and B proteins (CSA and CSB), RNA Polymerase II (Pol II) and XPA in response to DNA damage and is believed to function in the TCR pathway. HCNP also functions as an essential component of a pre-mRNA splicing complex of the spliceosome (composed of AQR (aquarius), PRP19, CCDC16, HCNP, ISY1 and |
Immunogen | Immunogen: Synthetic peptide of human XAB2 Immunogen Type: Peptide |
Other Names | [HCNP; HCRN; SYF1; NTC90] |
Gene, Accession # | [XAB2], Gene ID: 56949, NCBI: NP_064581.2, UniProt: Q9HCS7 |
Catalog # | MBS9417218 |
Price | $255 |
Order / More Info | XAB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |