Mimitin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMimitin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
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DescriptionMimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptos
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide from near the carboxy terminus of human Mimitin.
Other Names[NADH dehydroxygenase (ubiquinone) 1 alpha subcomplex, assembly factor 2, NDUFAF2, NDUFA12L, MMTN]
Gene, Accession #Gene ID: 91942, NCBI: NP_777549
Catalog #MBS9414867
Price$320
Order / More InfoMimitin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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