Phospho-HSP27 (Ser15) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-HSP27 (Ser15) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-HSP27 (Ser15) antibody detects endogenous levels of HSP27 only when phosphorylated at Serine 15. Description: HSP27 is a small heat shock protein that is regulated both transcriptionally and posttranslationally. Modulates actin polymerization and reorganization.Function: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).Subunit Structure: |
| Immunogen | Immunogen: A synthesized peptide derived from human HSP27 around the phosphorylation site of Serine 15 Subcellular Location: Cytoplasm. Nucleus. Cytoplasm > Cytoskeleton > Spindle. Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. Tissue Specificity: Detected in all tissues tested: skeletal muscle, heart, aorta, large intestin |
| Other Names | [Heat shock 27kDa protein; 28 kDa heat shock protein; CMT2F; DKFZp586P1322; epididymis secretory protein Li 102; Estrogen regulated 24 kDa protein; Estrogen-regulated 24 kDa protein; Heat shock 25kDa protein 1; Heat shock 27 kDa protein; Heat shock 27kD protein 1; Heat shock 27kDa protein 1; Heat shock 28kDa protein 1; Heat Shock Protein 27; Heat shock protein beta 1; Heat shock protein beta-1; heat shock protein family B (small) member 1; HEL-S-102; HMN2B; HS.76067; Hsp 25; HSP 27; Hsp 28; Hsp B1; Hsp25; HSP27; Hsp28; HspB1; HSPB1_HUMAN; SRP27; Stress responsive protein 27; Stress-responsive protein 27] |
| Gene, Accession # | [HSP27], Gene ID: 3315, NCBI: NP_001531.1, UniProt: P04792 |
| Catalog # | MBS9600852 |
| Price | $240, $280 |
| Order / More Info | Phospho-HSP27 (Ser15) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Xia F, Yao X, Tang W, Xiao C, Yang M, Zhou B; Journal: Front Pharmacol. Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)-Based Proteomic Analysis of Hugan Qingzhi and Its Protective Properties against Free Fatty Acid-Induced L02 Hepatocyte Injury. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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