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Antigenic Specificity | UBE1L |
Clone | [5B10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The modification of proteins with ubiquitin is an important cellular mechanism for targeting. Tissue specificity: Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-lik |
Immunogen | Immunogen: Purified recombinant fragment of human UBE1L expressed in E. Coli. |
Other Names | [D8; UBE2; UBA1B; UBE1L; MGC12713; UBA7] |
Gene, Accession # | [UBE1L], Gene ID: 7318, NCBI: NP_003326.2, UniProt: P41226 |
Catalog # | MBS8538674 |
Price | $280 |
Order / More Info | UBE1L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |