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Antigenic Specificity | Lrp8 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, sheep, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Lrp8. It was validated on Western BlotTarget Description: Lrp8 is the cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Lrp8 binds the endoplasmic reticulum resident receptor-associated protei |
Immunogen | Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse |
Other Names | [low-density lipoprotein receptor-related protein 8; low density lipoprotein receptor-related protein 8, apolipoprotein e receptor] |
Gene, Accession # | [LRP8], Gene ID: 16975, NCBI: NP_444303, UniProt: Q924X6 |
Catalog # | MBS3207310 |
Price | $335 |
Order / More Info | Lrp8 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |