KPNA6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | KPNA6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | KPNA6 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA6 belongs to a subfamily within the KPNA family that also includes IPOA5&6. Down-regulation of KPNA6 by RNAi expression in HeLa cells strongly inhibited cell proliferation, possibly due to blocking the nuclear import of specific factors essential for cell growth and proliferation. KPNA6 also interacts with the Rev protein of HIV-1 and |
| Immunogen | Immunogen: KPNA6 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human KPNA6. The immunogen is located within amino acids 70-120 of KPNA6. Buffer: KPNA6 Antibody is supplied in PBS containing 0.02% sodium azide. Positive Control: MBS151597- HEK293 Cell Lysate. MBS154185-HEK293 Cell Slide. |
| Other Names | [KPNA6; IPOA7; KPNA7; IPOA7; Importin subunit alpha-7; Karyopherin subunit alpha-6; karyopherin alpha 6 (importin alpha 7)], [KPNA6; KPNA6; IPOA7; KPNA7; IPOA7] |
| Gene, Accession # | [KPNA6], Gene ID: 23633, NCBI: CAH71948, UniProt: O60684 |
| Catalog # | MBS150717 |
| Price | $375 |
| Order / More Info | KPNA6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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