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Antigenic Specificity | LFG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. LFG is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, LFG is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. LFG, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. LFG is widely distributed, but highly expressed in the hippocampus and other neural tissues. LFG was |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide from near the amino terminus of human LFG. |
Other Names | [Lifeguard, Fas apoptotic inhibitory molecule2, FAIM2, NMP35] |
Gene, Accession # | [LFG], NCBI: AAF06327 |
Catalog # | MBS9408304 |
Price | $320 |
Order / More Info | LFG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |