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Antigenic Specificity | Jarid1c |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect Jarid 1c in human and mouse samples. Background: Jarid1c is a histone demethylase which specifically demethylates lysine 4 of histone H3, thereby playing a central role in the regulation of transcription and chromatin remodelling. Jarid1c demethylates the trimethylated and dimethylated lysine 4, but not the monomethylated form. Further, Jarid1c participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in the Jarid1c gene have been associated with X-linked mental retardation. |
Immunogen | Immunogen: Polyclonal antibody raised in rabbit against mouse Jarid1c (jumonji, AT rich interactive domain 1C), using 3 KLH-conjugated synthetic peptides containing sequences from the inner part of the protein. Positive Control: Western blot: HeLa cells, ELISA: Peptides. |
Other Names | [KDM5C; MRXJ; MRXSJ; SMCX; XE169], [KDM5C; KDM5C; MRXJ; SMCX; MRX13; MRXSJ; XE169; MRXSCJ; JARID1C; DXS1272E; DXS1272E; JARID1C; SMCX; XE169] |
Gene, Accession # | Gene ID: 8242, NCBI: NP_001140174.1, UniProt: P41229 |
Catalog # | MBS840467 |
Price | $235 |
Order / More Info | Jarid1c Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |