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Antigenic Specificity | Grp78 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Grp78 protein. When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM] |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment corresponding to a region within amino acids 478 and 654 of Grp78. |
Other Names | [BIP; FLJ26106; GRP78; MIF2; HSPA5; immunoglobulin heavy chain-binding protein; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; heat shoc] |
Gene, Accession # | [Grp78], Gene ID: 3309, NCBI: NP_005338.1, UniProt: P11021 |
Catalog # | MBS9411281 |
Price | $320 |
Order / More Info | Grp78 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |