CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL) |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises cholesterol 24-hydroxylase (CYP46A1), a 58 kDa member of the Cytochrome P450 family, expressed in the brain. CYP46A1 converts cholesterol into the biologically active oxysterol and 24(S)-hydroxycholesterol, in the first step of the enzymatic degradation of cholesterol in the brain. CYP46A1 is also thought to play a role in the metabolism of neurosteroids and drugs that can cross the blood-brain barrier and are targeted to the central nervous system.. . P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug |
| Immunogen | Immunogen: Synthetic peptide corresponding to amino acid sequence 254-270 of human cholesterol 24-hydroxylase protein. Antiserum Preparation: Antisera to cholesterol 24-hydroxylase (CT) were raised by repeated immunisations of goats with highly purified antigen. Target Species: Human |
| Other Names | [cholesterol 24-hydroxylase; Cholesterol 24-hydroxylase; cholesterol 24-hydroxylase; CH24H; cytochrome P450 46A1; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase); cytochrome P450, family 46, subfamily A, polypeptide 1; Cytochrome P450 46A1], [CYP46A1; CYP46A1; CP46; CYP46; CYP46; CH24H] |
| Gene, Accession # | Gene ID: 10858, NCBI: NP_006659.1, UniProt: Q9Y6A2 |
| Catalog # | MBS222345 |
| Price | $470 |
| Order / More Info | CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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