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Antigenic Specificity | Human AGGRECAN |
Clone | [7D4] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, ELISA (EIA), Immunoprecipitation (IP), Immunohistology Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human Aggrecan antibody, clone 7D4 recognizes human aggrecan, a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS). Studies using a panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. These studies also showed a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues (Virgintino et al. 2009). Mouse anti Human Aggrecan antibody, clone 7D4 recognizes epitopes within the N-terminal G1-IGD-G2 region of aggrecan, |
Immunogen | Immunogen: Purified human articular cartilage aggrecan Histology Positive Control Tissue: Cerebral Cortex Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the mouse NS1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [Aggrecan core protein; Aggrecan core protein; aggrecan core protein; cartilage-specific proteoglycan core protein; chondroitin sulfate proteoglycan core protein 1; large aggregating proteoglycan; aggrecan; Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1], [ACAN; ACAN; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP; AGC1; CSPG1; MSK16; CSPCP; Chondroitin sulfate proteoglycan 1] |
Gene, Accession # | Gene ID: 176, NCBI: P16112.2, UniProt: P16112 |
Catalog # | MBS224511 |
Price | $475 |
Order / More Info | Human AGGRECAN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |