APOBEC3A/B Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | APOBEC3A/B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: APOBEC3A/B antibody detects endogenous levels of total APOBEC3A/B. Function: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.Subunit Structure: Interacts with AGO2. Interacts with TRI |
| Immunogen | Immunogen: A synthesized peptide derived from human APOBEC3A/B Subcellular Location: Nucleus Tissue Specificity: Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells. Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues including lung and adipose tissues. Found at high levels in colorectal adenocarcinoma, Burkitt's lymphoma and chronic myelogenous leukemia. Predicted Cross Reactivity: Rabbit Similarity: R |
| Other Names | [A3A; ABC3A_HUMAN; APOBEC3A; Apolipoprotein B mRNA editing enzyme; Apolipoprotein B mRNA editing enzyme, catalytic polypeptide like 3A; ARP3; bK150C2.1; Catalytic polypeptide like 3A; Phorbolin 1; Phorbolin-1; PHRBN; Probable DNA dC > dU editing enzyme APOBEC-3A; Probable DNA dC-> dU-editing enzyme APOBEC-3A; A3B; APOBEC1L; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3B; ARCD3; ARP4; bK150C2.2; Cytidine deaminase; DJ742C19.2; DNA dC-> dU-editing enzyme APOBEC-3B; FLJ21201; Phorbolin 1 related protein; Phorbolin 2; Phorbolin 2/3; Phorbolin 3; PHRBNL; Probable DNA dC> dU editing enzyme APOBEC3B] |
| Gene, Accession # | [APOBEC3A], Gene ID: 100913187, NCBI: NP_001180218.1, UniProt: P31941 |
| Catalog # | MBS9610093 |
| Price | $240, $280 |
| Order / More Info | APOBEC3A/B Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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