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Antigenic Specificity | CD20 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~34 kDa of human CD20. The other species are not tested. CD20, a non-glycosylated protein, belongs to a member of the membrane-spanning 4A gene family. The molecular weight is at a range of ~34-37kDa depending on the degree of the protein phosphorylation. The CD20 antigen is present on human pre B lymphocytes and B lymphocytes at all stages of maturation. Thus, it plays an important role in the development and differentiation of B-cells into plasma cells. Low level of CD20 expression appears on normal T lymphocytes. Combination of chemo and humanized CD20 antibodies has been reported in clinical study of lymphoma diseases. |
Immunogen | n/a |
Other Names | [MS4A1; CD20; CD20 antigen; CD20 receptor; B-Lymphocyte cell-surface antigen B1], [MS4A1; MS4A1; CD20; CD20] |
Gene, Accession # | [CD20], Gene ID: 485430, NCBI: BAE47068.1 |
Catalog # | MBS460043 |
Price | $285 |
Order / More Info | CD20 Antibody from MYBIOSOURCE INC. |
Product Specific References | Smith MR, Rituximab (monoclonal anti-CD20 antibody: mechanisms of action and resistance. Oncogene, 2003 Oct 20;22 (47):7359-68. |