NSMCE4A - C-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNSMCE4A - C-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunofluorescence (IF), Western Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against NSMCE4A. It was validated on Western BlotTarget Description: NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
Other Names[non-structural maintenance of chromosomes element 4 homolog A isoform 1; Non-structural maintenance of chromosomes element 4 homolog A; non-structural maintenance of chromosomes element 4 homolog A; NSE4 homolog A, SMC5-SMC6 complex component]
Gene, Accession #[NSMCE4A], Gene ID: 54780, NCBI: NP_060085, UniProt: Q9NXX6
Catalog #MBS3218681
Price$365
Order / More InfoNSMCE4A - C-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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