DDB2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | DDB2 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for DNA damage-binding protein 2(DDB2) detection. Tested with WB in Human. Background: DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sens |
| Immunogen | Immunogen: E Coli-derived human DDB2 recombinant protein (Position: M1-T115). Human DDB2 shares 58.3% amino acid (aa) sequence identity with mouse DDB2. Ig Type: Rabbit IgG |
| Other Names | [DNA damage-binding protein 2; damage-specific DNA binding protein 2; Damage-specific DNA-binding protein 2; DDB p48 subunit; Ddb2; DDB2_HUMAN; DDBb; DNA damage-binding protein 2; UV-damaged DNA-binding protein 2; UV-DDB 2; Xeroderma pigmentosum group E protei; damage-specific DNA binding protein 2], [DDB2; DDB2; XPE; DDBB; UV-DDB2; DDBb; UV-DDB 2] |
| Gene, Accession # | [DDB2], Gene ID: 1643, NCBI: NP_000098.1, UniProt: Q92466 |
| Catalog # | MBS178304 |
| Price | $280 |
| Order / More Info | DDB2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: DDB2 damage-specific DNA binding protein 2, 48kDa. 2. Dualan R, Brody T, Keeney S, Nichols AF, Admon A, Linn S (Sep 1995). Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein. Genomics 29 (1): 62-9. 3. Keeney S, Chang GJ, Linn S (Oct 1993). Characterization of a human DNA damage binding protein implicated in xeroderma pigmentosum E. The Journal of Biological Chemistry 268 (28): 21293-300. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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