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Antigenic Specificity | STK10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: STK10 antibody detects endogenous levels of total STK10. Function: Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.Subunit Structure: Homodimer; homodimerization is required for activation segment autophosphorylation.Post-translational Modifications: Autophosphorylates following homodimerization, leading to activation of the protein. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Plasma Membrane Tissue Specificity: Highly expressed in rapidly proliferating tissues (spleen, placenta, and peripheral blood leukocytes). Also expressed in brain, heart, skeletal muscle, colon, thymus, kidney, liver, small intestine and lung. |
Other Names | [LOK; Lymphocyte oriented kinase; Lymphocyte-oriented kinase; PRO2729; Serine threonine protein kinase 10; Serine/threonine-protein kinase 10; STK10; STK10_HUMAN] |
Gene, Accession # | [STK10], Gene ID: 6793, NCBI: NP_005981.3, UniProt: O94804 |
Catalog # | MBS9606237 |
Price | $240, $280 |
Order / More Info | STK10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |