Presenilin 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPresenilin 1
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Presenilin 1 antibody detects endogenous levels of total Presenilin 1. PSEN1 probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Regulates epithelial-cadherin function.
ImmunogenImmunogen: A synthesized peptide derived from human Presenilin 1
Other Names[AD3; FAD; presenilin 1; Presenilin-1; Presenilin-1 CTF subunit; Presenilin-1 CTF12; Presenilin-1 NTF subunit; Protein S182; PS-1; PS1; PS1-CTF12; PSN1; PSNL1; S182]
Gene, Accession #[PSEN1], Gene ID: 5663, NCBI: NP_000012.1, UniProt: P49768
Catalog #MBS8510739
Price$290
Order / More InfoPresenilin 1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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