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Antigenic Specificity | Presenilin 1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Presenilin 1 antibody detects endogenous levels of total Presenilin 1. PSEN1 probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Regulates epithelial-cadherin function. |
Immunogen | Immunogen: A synthesized peptide derived from human Presenilin 1 |
Other Names | [AD3; FAD; presenilin 1; Presenilin-1; Presenilin-1 CTF subunit; Presenilin-1 CTF12; Presenilin-1 NTF subunit; Protein S182; PS-1; PS1; PS1-CTF12; PSN1; PSNL1; S182] |
Gene, Accession # | [PSEN1], Gene ID: 5663, NCBI: NP_000012.1, UniProt: P49768 |
Catalog # | MBS8510739 |
Price | $290 |
Order / More Info | Presenilin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |