SYT1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SYT1 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | SYT1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Synaptotagmin 1 (SYT1) is an integral membrane protein found in synaptic vesicles thought to play a role in vesicle trafficking and exocytosis (1). Individual SYT1 proteins are composed of an amino-terminal transmembrane region, a central linker region and a pair of carboxy-terminal C2 domains responsible for binding Ca2+ (2). The C2 domains appear to be functionally distinct, with the C2A domain responsible for regulating synaptic vesicle fusion in a calcium-dependent manner during exocytosis while the C2B domain allows for interaction between adjacent SYT1 proteins (3). Because synaptotagmin 1 binds calcium and is found in synaptic vesicles, this integral membrane protein is thought act as a calcium sensor in fast synaptic vesicle exocyto |
| Immunogen | Immunogen: Recombinant protein of human SYT1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [SYT1; DKFZp781D2042; P65; SVP65; SYT] |
| Gene, Accession # | [SYT1], Gene ID: 6857, NCBI: NP_001129277.1, UniProt: P21579 |
| Catalog # | MBS8501430 |
| Price | $310 |
| Order / More Info | SYT1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Fukuda, M. and Mikoshiba, K. (2001) Biochem Biophys Res Commun 281, 1226-33. 2. Sudhof, T.C. (2002) J Biol Chem 277, 7629-32. 3. Fernandez-Chacon, R. et al. (2001) Nature 410, 41-9. 4. Lynch, K.L. et al. (2007) Mol Biol Cell 18, 4957-68. 5. Gauthier, B.R. and Wollheim, C.B. (2008) Am J Physiol Endocrinol Metab 295, E1279-86. 6. Bai, J. et al. (2004) Neuron 41, 929-42. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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