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Antigenic Specificity | APPL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.4 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total APPL1 protein. The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
Other Names | [APPL; DIP13alpha] |
Gene, Accession # | [APPL1], Gene ID: 26060, NCBI: NP_036228.1, UniProt: Q9UKG1 |
Catalog # | MBS9401655 |
Price | $255 |
Order / More Info | APPL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |