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Antigenic Specificity | B2M |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: B2M antibody detects endogenous levels of total B2M. Description: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1, 2). As an integral component of the MHC class I complex, beta2-microglobulin plays a critically important role in immune system function (3). It has important relevance to cancer biology research; for example, research studies have shown that nearly one-third of diffuse large B cell lymphomas contain mutations that inactivate beta2-microglobulin gene function, thereby allo |
Immunogen | Immunogen: A synthesized peptide derived from human B2M Subcellular Location: Secreted. Detected in serum and urine. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (92%) |
Other Names | [B2M; B2MG_HUMAN; Beta 2 microglobin; Beta 2 microglobulin; Beta 2 microglobulin precursor; Beta chain of mhc class 1 proteins; Beta chain of MHC class I molecules; Beta-2-microglobulin form pI 5.3; CDABP0092; Hdcma22p] |
Gene, Accession # | [B2M], Gene ID: 567, NCBI: NP_004039.1, UniProt: P61769 |
Catalog # | MBS9607114 |
Price | $240, $280 |
Order / More Info | B2M Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |