Edit |   |
Antigenic Specificity | Androgen Receptor (Marker of Androgen Dependence) |
Clone | [AR441 + DHTR/882] |
Host Species | Mouse |
Reactive Species | human. does not react with mouse. |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in th |
Immunogen | Immunogen: A synthetic peptide, aa 302-318 of human AR (AR441); Recombinant human DHTR protein (DHTR/882) |
Other Names | [AIS; Dihydrotestosterone receptor (DHTR); HUMARA; HYSP1; Kennedy disease (KD); Nuclear receptor subfamily 3 group C member 4 (NR3C4); SMAX1; Spinal and bulbar muscular atrophy (SBMA); Testicular Feminization (TFM)], [AR; AR; KD; AIS; AR8; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; DHTR; NR3C4] |
Gene, Accession # | [AR], Gene ID: 367, NCBI: NP_000035.2, UniProt: P10275 |
Catalog # | MBS438516 |
Price | $190, $340, $340 |
Order / More Info | Androgen Receptor (Marker of Androgen Dependence) Antibody from MYBIOSOURCE INC. |
Product Specific References | J-nne OA, et al. Androgen receptor and mechanism of androgen action. Ann Med 1993; 25:8 |